ShereKhan—calculating exchange parameters in relaxation dispersion data from CPMG experiments

Mazur A, Hammesfahr B, Griesinger C, Lee D, Kollmar M

Bioinformatics 29, 1819-1820 (2013)

SUMMARY: Dynamics governing the function of biomolecule is usually described as exchange processes and can be monitored at atomic resolution with nuclear magnetic resonance (NMR) relaxation dispersion data. Here, we present a new tool for the analysis of CPMG relaxation dispersion profiles (ShereKhan). The web interface to ShereKhan provides a user-friendly environment for the analysis. AVAILABILITY: A stable version of ShereKhan, the web application and documentation are available at http://sherekhan.bionmr.org.

PubMed Journal